PKUMDL-WQ-2201 is a PHGDH non-NAD-competing allosteric inhibitor with micromolar potency against wild-type and mutant PHGDH enzymes, effectively suppressing de novo serine biosynthesis in cancer cells and reducing tumor growth, PKUMDL-WQ-2201 provide a metabolic intervention strategy for studying serine-dependent tumor metabolism.
Molekulargewicht:
351.81
Reinheit:
95.41%
CAS Nummer:
[592474-91-4]
Formel:
C15H14ClN3O3S
Target-Kategorie:
Dehydrogenase
T28425
T28425
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
