UNC9994 hydrochloride is a functionally selective, beta-arrestin-biased dopamine D2 receptor (D2R) agonist with a Ki of 79 nM for D2R binding. UNC9994 hydrochloride also acts as an antagonist of Gi-regulated cAMP production and a partial agonist for D2R/beta-arrestin-2 interactions, exhibiting potent antipsychotic-like activity.
Molekulargewicht:
457.84
CAS Nummer:
[2108826-33-9]
Formel:
C21H23Cl3N2OS
Target-Kategorie:
Arrestin|||Dopamine Receptor
T62853
T62853
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