QM295 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) characterized by its selectively reversible thiol reactivity. ERO1 is a key enzyme in the endoplasmic reticulum of eukaryotic cells responsible for catalyzing disulfide bond formation, which is essential for proper protein folding. QM295 inhibits ERO1 activity by interacting with specific thiol groups. It serves as an effective pharmacological tool for investigating endoplasmic reticulum stress (ER stress) and the mechanisms of oxidative protein folding.
Molekulargewicht:
295.29
Reinheit:
99.35%
CAS Nummer:
[1241046-32-1]
Formel:
C17H13NO4
Target-Kategorie:
Others
T73536
T73536
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