Mcl-1 inhibitor 17 is an effective inhibitor of the Mcl-1 protein. Mcl-1 is a critical anti-apoptotic member of the Bcl-2 family, frequently overexpressed in various malignancies, where it suppresses apoptosis by sequestering pro-apoptotic proteins such as Bak and Bax. Mcl-1 inhibitor 17 functions by competitively binding to the BH3-binding groove of Mcl-1, thereby releasing pro-apoptotic factors and restoring apoptotic sensitivity in cancer cells. This compound is utilized for research into cancer and other diseases associated with Mcl-1 dysregulation.
Molekulargewicht:
456.51
Reinheit:
99.96%
CAS Nummer:
[892250-00-9]
Formel:
C27H25FN4O2
Target-Kategorie:
Bcl-2 Family
T84800
T84800
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