Myosin-IN-1 (compound F10), a specific inhibitor of cardiac myosin, acts by stabilizing the cardiac myosin motor domain in its closed biochemical and structural state. Myosin-IN-1 (compound F10) reduces myocardial force production and calcium sensitivity, functioning as a negative inotropic agent. In isolated Langendorff-perfused rat hearts, Myosin-IN-1 decreases stress in myofilaments and diminishes the development of left ventricular pressure, and applicable in heart failure research.
Molekulargewicht:
296.41
Reinheit:
99.81%
CAS Nummer:
[849011-39-8]
Formel:
C12H16N4OS2
Target-Kategorie:
Myosin
T86938
T86938
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