TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 µM. It is utilized in research focused on gastric cancer.
Molekulargewicht:
337.81
CAS Nummer:
[1389439-77-3]
Formel:
C18H16ClN5
Target-Kategorie:
Aurora Kinase
T89833
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