GDC-0425, CAS [[1200129-48-1]]
Artikelnummer:
TGM-T9666
- Bilder (2)
| Artikelname: | GDC-0425, CAS [[1200129-48-1]] |
| Artikelnummer: | TGM-T9666 |
| Hersteller Artikelnummer: | T9666 |
| Alternativnummer: | TGM-T9666-2MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | RG-7602 |
| GDC-0425 (RG-7602) is a potent and highly selective inhibitor of Checkpoint kinase 1 (Chk1). This product blocks DNA damage-induced cell cycle arrest by inhibiting Chk1 activity, forcing damaged cells into mitosis and ultimately leading to apoptosis. Research indicates that the activity of GDC-0425 is modulated by the Ras-MEK signaling pathway, and it significantly enhances tumor regression when combined with DNA-damaging agents like Gemcitabine. |
| Molekulargewicht: | 321.38 |
| CAS Nummer: | [1200129-48-1] |
| Formel: | C18H19N5O |
| Target-Kategorie: | Others |
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T9666 |
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T9666 |
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