28-Deoxonimbolide is a nimbolide-type limonoid natural product isolated from the seeds of Azadirachta indica. In vitro, it induces apoptosis in tumor cells (e.g., HL-60), with mechanisms involving mitochondrial pathways and potentially the participation of death receptor signaling. It is commonly used in studies of anticancer mechanisms.
Molekulargewicht:
452.55
CAS Nummer:
[126005-94-5]
Formel:
C27H32O6
Target-Kategorie:
Apoptosis|||Caspase
TN2835
TN2835
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