alpha-Ionone acts as an agonist for the olfactory receptor OR10A6. It induces apoptosis by activating OR10A6 and increasing the phosphorylation level of the LATS-YAP-TAZ signaling axis in the Hippo pathway, thereby inhibiting tumorigenesis and tumor progression in both in vitro and in vivo experiments.
Molekulargewicht:
192.3
CAS Nummer:
[127-41-3]
Formel:
C13H20O
Target-Kategorie:
YAP
TN3385
TN3385
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