Cholesterol-25-Hydroxylase (CH25H) BioAssay(TM) ELISA Kit (Human)
Artikelnummer:
USB-024121
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| Artikelname: | Cholesterol-25-Hydroxylase (CH25H) BioAssay(TM) ELISA Kit (Human) |
| Artikelnummer: | USB-024121 |
| Hersteller Artikelnummer: | 024121 |
| Alternativnummer: | USB-024121-96 |
| Hersteller: | US Biological |
| Kategorie: | Kits/Assays |
| Cholesterol-25-Hydroxylase (CH25H) BioAssay(TM) ELISA Kit (Human) is a sandwich enzyme immunoassay for in vitro quantitative measurement of CH25H in human serum, plasma, tissue homogenates and other biological fluids. Detection Range: 0.625-40ng/ml Sensitivity: 0.226ng/ml Cholesterol-25-Hydroxylase (CH25H) is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. The deduced 272-amino acid peptide has characteristics of a polytopic membrane protein and contains clusters of histidine residues essential for catalytic activity. Northern blot analysis showed very low levels of cholesterol 25-hydroxylase mRNA in 16 different tissues. Immunohistochemistry detected cholesterol 25-hydroxylase in the endoplasmic reticulum and a perinuclear compartment of transfected cells. HGNC 1907 MGI 1333869 OMIM 604551 RGD 1310575 UCSC uc001kfz.2 UniProt O95992 Storage and Stability: Desiccation recommended. The Standard, Detection Reagent A, Detection Reagent B and the 96-well strip plate should be stored at -20C upon receipt. Store all other reagents at 4C. Stable for 6 months after receipt of order. |
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