TSPAN7, as known as tetraspanin-7, is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Also, it is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntingtons chorea, fragile X syndrome and myotonic dystrophy. More recently, it has been identified as a key immune system target in type 1 diabetes. Source: Recombinant protein corresponding to aa113-213 from human TSPAN7, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~12.6kD (110aa) 13.5-18kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: ADPRHEIKDT FLRTYTDAMQ TYNGNDERSR AVDHVQRSLS CCGVQNYTNW STSPYFLEHG IPPSCCMNET DCNPQDLHNL TVAATKVNQK GCYDLVTSFM ETNMHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
