E. coli-expressed amino acid 1-69 of mature rat MIP-1a
MIP-1a (macrophage inflammatory protein-1 a) is a 69-amino acid CC chemokine with a molecular weight of 7.9kD. MIP-1a induces migration of monocytes/macropages, B lymphocytes, activated CD8+ T cells, natural killer (NK) cells, eosinophils3,4. MIP-1a also stimulates basophils to release histamine, induces ICAM-1 expression, mast cell degranulation, and production of TNFa, IL-1 and IL-6. In addition to its proinflammatory activities, MIP-1a inhibits the proliferation of hematopoietic stem cells in vitro and in vivo. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Immunoprecipitation: 1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Reinheit:
Purified by Protein A affinity chromatography.
Formulierung:
Supplied as a lyophilized powder in 0.09% sodium azide.
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