Monoclonal antibody to CD247/CD3 Zeta (TCR, CD3) (Clone: 6B10.2)
Biozol Catalog Number:
ABI-10-4901
Supplier Catalog Number:
10-4901
Alternative Catalog Number:
ABI-10-4901-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Immunogen:
Human TCR zeta chain aa38-54
Alternative Names:
T-cell receptor T3 zeta chain, CD247, CD3zeta, CD3Z, T3Z, TCRZ
The invariant TCR zeta chain is a member of the CD3 complex associated with the clonotypic alpha/beta TCR heterodimer. The disulfide-linked TCR zeta homodimers transmit signals following TCR ligation. Loss of TCR zeta expression has been reported in a diverse range of disease states, including autoimmune diseases, many neoplastic conditions and chronic infections, such as tuberculosis and leprosy.
Figure-1: Western blot analysis of CD247. Anti-CD247 antibody (Clone: 6B10.2) was used at 1 µg/ml on (1) Jurkat, (2) Daudi and (3) Raw lysates. Jurkat showing high expression and Daudi, Raw showing no expressions.
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