Specificity: Rabbit Anti-Severe Acute Respiratory Syndrome Spike (SARS Spike) recognizes an epitope near the N-terminus of SARS Spike. This polyclonal antibody was purified using affinity chromatography. Background: A coronavirus, SARS (Severe Acute Respiratory Syndrome), was first identified 2002-2003. Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately in length. SARS can be mediated by the binding of the viral spike protein, a glycosylated protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.
Clonality:
Polyclonal
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