The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin&39s disease tissue and might participate in the interaction between the HandRS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and:or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
