The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Clonality:
Monoclonal
Clone Designation:
[DM130]
Purity:
Purified from cell culture supernatant by affinity chromatography
Target:
EGFR
Antibody Type:
Recombinant Antibody
Application Dilute:
ELISA 1/5000-10000,FACS 1/100
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