Human ERBB2 scFv-TM-4-1BB-CD3z (tEGFR)

Catalog Number: ABN-U1092
Article Name: Human ERBB2 scFv-TM-4-1BB-CD3z (tEGFR)
Biozol Catalog Number: ABN-U1092
Supplier Catalog Number: U1092
Alternative Catalog Number: ABN-U1092-1
Manufacturer: Abnova
Host: Human
Category: Sonstiges
Application: Cytotoxic Assay, FC
Human CAR-T cells express an anti-HER2 CAR containing a HER2-specific scFv, hinge and transmembrane domains, the 4-1BB costimulatory domain and the CD3zeta activation domain, and additionally express truncated EGFR driven by a separate promoter for Cetuximab-mediated deletion by ADCC.
UniProt: 2064
Buffer: In 90% FBS, 10% DMSO
Form: Liquid
Target: ERBB2