Polatuzumab is a genetically engineered humanized monoclonal antibody directed against the CD79b antigen (Bcell receptor complexassociated protein beta chain) found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine complementaritydetermining region (CDR) sequences grafted into human framework regions of the variable domains and human constant region sequences. Polatuzumab is composed of two heavy chains of 452 amino acids and two light chains of 214 amino acids. - Antikörper
Tag:
Mouse IgG1 | Mouse Kappa
Buffer:
PBS (pH 7.4)
Purity:
0.95
Form:
Powder
Target:
Polatuzumab
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