A synthesized peptide derived from human KMT5A / SETD8 / Pr-SET7 Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates Lys-20 of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.
Alternative Names:
N-lysine methyltransferase KMT5A, 2.1.1.-, H4-K20-HMTase KMT5A, Histone-lysine N-methyltransferase KMT5A, 2.1.1.361, Lysine N-methyltransferase 5A, Lysine-specific methylase 5A {ECO:0000312|HGNC:HGNC:29489}, PR/SET domain-containing protein 07, PR-Set7, PR/SET07, SET domain-containing protein 8, KMT5A (HGNC:29489)
Anti-KMT5A / SETD8 / Pr-SET7 Monoclonal Antibody . Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Clonality:
Monoclonal
Concentration:
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.