ZFYVE19 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP53381
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| Article Name: | ZFYVE19 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP53381 |
| Supplier Catalog Number: | AP53381 |
| Alternative Catalog Number: | ABT-AP53381-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human |
| Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. |
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