Recombinant RNase R (E. coli) is a magnesium-dependent 3'5' exoribonuclease that can digest all linear RNAs but does not digest lariat or circular RNA structures. Most cellular RNAs will be digested completely by RNase R, with the exception of tRNAs, 5S RNA and intron lariats.
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Nucleic Acid Extraction and Purification
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