DMOG (Dimethyloxaloyl glycine) is an antagonist of alpha-ketoglutarate cofactor and a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1alpha stabilisation and accmulation in vitro and in vivo. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.
Molecular Weight:
175.14
Purity:
99.53%
CAS Number:
[89464-63-1]
Formula:
C6H9NO5
Target:
HIF
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