ARV-766 is an orally active and potent proteolysis targeting chimera (PROTAC) protein degrader. ARV-766 degrades wild-type androgen receptor (AR) but also relevant AR LBD mutants, including the most prevalent AR L702H, H875Y, and T878A mutations. ARV-766 has the potential to be first- and best-in class PROTAC AR degrader in mCRPC.
Molecular Weight:
807.95
Purity:
>99.0%
CAS Number:
[2750830-09-0]
Formula:
C45H54FN7O6
Target:
PROTAC
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