Dapivirine is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations.
Molecular Weight:
329.4
Purity:
>99.0%
CAS Number:
[244767-67-7]
Formula:
C20H19N5
Target:
Reverse Transcriptase
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