The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D2
Alternative Names:
UBC4, PUBC1, UBCH4, UBC4/5, UBCH5B, E2(17)KB2
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Lanes: 1: 40ng HIS-UBE2D1 protein 2: 40ng HIS-UBE2D2 protein 3: 40ng HIS-UBE2D3 protein 4: 40ng HIS-UBE2D4 protein 5: 40ng HIS-UBE2E1 protein 6: 40ng HIS-UBE2E2 protein 7: 40ng HIS-UBE2E3 protein 8: 40ng HIS-UBE2K protein 9: 40ng HIS-UBE2L3 protein 10: 40ng HIS-UBE2N protein 11: 40ng HIS-UBE2V1 protein 12: 40ng HIS-UBE2V2 protein. Primary Antibody Dilution: 1:500 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:50,000 Gene Name: UBE2D2 Submitted by: Dr Chris Boutell. MRC-UoG Centre for Virus Research (CVR), UK.
UBE2D2 antibody - N-terminal region (ARP43007_P050) in Human Brain using Western Blot
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