Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human ABCE1
Alternative Names:
RLI, OABP, RLI1, ABC38, RNS4I, RNASEL1, RNASELI
ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-ABCE1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Jurkat cell lysateABCE1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
Researcher: Dr. Hao Zhu, University of Kansas Medical Center Application: Western blotting Species + Tissue/Cell type: Mouse liver extract How many ugs of tissue/cell lysate run on the gel: 1. 60 ug mouse liver extract 2. 60 ug mouse liver extract 3. 60 ug mouse liver extract Primary antibody dilution: 1:500 Secondary antibody: Anti-rabbit HRP Secondary antibody dilution: 1:3000
ABCE1 antibody - C-terminal region (ARP43633_P050) in Human Jurkat using Western Blot
* VAT and and shipping costs not included. Errors and price changes excepted