ABCB8 Antibody - middle region

Catalog Number: ASB-ARP43673_P050
Article Name: ABCB8 Antibody - middle region
Biozol Catalog Number: ASB-ARP43673_P050
Supplier Catalog Number: ARP43673_P050
Alternative Catalog Number: ASB-ARP43673_P050-25UL,ASB-ARP43673_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABCB8
Alternative Names: MABC1, M-ABC1, MITOSUR, EST328128
The membrane-associated protein ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCB8 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined, however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined, however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 79kDa
NCBI: 11194
UniProt: Q9NUT2
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-ABCB8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human heart
Host: Rabbit
Target: ABCB8
Positive control (+): Human Fetal Heart (HE)
Negative control (-): HepG2 Cell Lysate (HG)
Antibody concentration: 1ug/ml
ABCB8 antibody - middle region (ARP43673_P050) in Human Heart using Western Blot