Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Alternative Names:
FPS, FPPS, POROK9
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Host: Rabbit Target Name: FDPS Antibody Dilution: 1.0ug/ml Sample Type: COLO205 cell lysateFDPS is supported by BioGPS gene expression data to be expressed in COLO205
FDPS antibody - C-terminal region (ARP60781_P050) in Human COLO205 using Western Blot
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