TNFSF8 Antibody - N-terminal region

Catalog Number: ASB-ARP63790_P050
Article Name: TNFSF8 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP63790_P050
Supplier Catalog Number: ARP63790_P050
Alternative Catalog Number: ASB-ARP63790_P050-25UL,ASB-ARP63790_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Alternative Names: CD153, CD30L, CD30LG, TNLG3A
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkins and some non-Hodgkins lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 26kDa
NCBI: 944
UniProt: P32971
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-TNFSF8 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal kidney
Host: Rabbit
Target Name: TNFSF8
Sample Type: Human Daudi
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1.0 ug/ml
Peptide Concentration: 2.0 ug/ml
Lysate Quantity: 25 ug/lane
TNFSF8 antibody - N-terminal region (ARP63790_P050) in Human Fetal Kidney using Western Blot