GPR68 Antibody - middle region
Catalog Number:
ASB-ARP64436_P050
- Images (3)
| Article Name: | GPR68 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP64436_P050 |
| Supplier Catalog Number: | ARP64436_P050 |
| Alternative Catalog Number: | ASB-ARP64436_P050-25UL,ASB-ARP64436_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of Human GPR68 |
| Alternative Names: | OGR1, AI2A6, GPR12A |
| Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer. |



