CCR8 Antibody - middle region

Catalog Number: ASB-AVARP09059_T100
Article Name: CCR8 Antibody - middle region
Biozol Catalog Number: ASB-AVARP09059_T100
Supplier Catalog Number: AVARP09059_T100
Alternative Catalog Number: ASB-AVARP09059_T100-25UL,ASB-AVARP09059_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Human, Rabbit
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCR8
Alternative Names: CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8
CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 41kDa
NCBI: 1237
UniProt: P51685
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-CCR8 Antibody Titration: 2.5ug/ml
Positive Control: K562 cell lysateCCR8 is supported by BioGPS gene expression data to be expressed in K562
Host: Rabbit
Target Name: CCR8
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml
CCR8 antibody - middle region (AVARP09059_T100) in Human K562 using Western Blot