CFB Antibody - middle region
Catalog Number:
ASB-OAAB05624
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| Article Name: | CFB Antibody - middle region |
| Biozol Catalog Number: | ASB-OAAB05624 |
| Supplier Catalog Number: | OAAB05624 |
| Alternative Catalog Number: | ASB-OAAB05624-400UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | FC, IHC-P, WB |
| Species Reactivity: | Human |
| Immunogen: | This CFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-494 amino acids from the Central region of human CFB. |
| Alternative Names: | BF, FB, BFD, GBG, CFAB, CFBD, PBF2, AHUS4, FBI12, H2-Bf, ARMD14 |
| CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. |
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