TCEB3 (NP_003189, 81 a.a. ~ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Alternative Names:
elongin 110 kDa subunit,elongin-A,RNA polymerase II transcription factor SIII subunit A1,SIII,SIII p110,TCEB3,TCEB3A,transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A),transcription elongation factor B alpha subunit,transcription elongation factor B polypeptide 3,transcription elongation factor B subunit 3.
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq
