family of interleukin 1-theta,FIL1 theta,FIL1-theta,FKSG75,IL-1 theta,IL-1F10 (canonical form IL-1F10a),IL1HY2,IL-1HY2,IL1-theta,IL-38,interleukin 1 family member 10 (theta),interleukin-1 family member 10,interleukin-1 HY2,interleukin-1 receptor antagonist FKSG75,interleukin-1 receptor antagonist-like FIL1 theta,Interleukin-1 theta,interleukin-38.
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
