PMAIP1 Antibody
Catalog Number:
ASB-OACA09447
- Images (3)
| Article Name: | PMAIP1 Antibody |
| Biozol Catalog Number: | ASB-OACA09447 |
| Supplier Catalog Number: | OACA09447 |
| Alternative Catalog Number: | ASB-OACA09447-100UG,ASB-OACA09447-50UG |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IF, IHC |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1 protein (1-136AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | adult T cell leukemia-derived PMA-responsive,APR,immediate-early-response protein APR,NOXA,phorbol-12-myristate-13-acetate-induced protein 1,PMA-induced protein 1,protein Noxa. |
| Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
| Clonality: | Polyclonal |
| NCBI: | 5366 |
| Purity: | >95% |
| Form: | Liquid |
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Immunofluorescent analysis of HeLa cells at dilution of 1:100 and Alexa Fluor 488-conguga |
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Immunohistochemistry of paraffin-embedded human heart tissue at dilution of 1:100 |
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Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100 |
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