ZNF365 Antibody

Catalog Number: ASB-OACA09592
Article Name: ZNF365 Antibody
Biozol Catalog Number: ASB-OACA09592
Supplier Catalog Number: OACA09592
Alternative Catalog Number: ASB-OACA09592-100UG,ASB-OACA09592-50UG
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IF, IHC
Species Reactivity: Human
Immunogen: Recombinant Human Protein ZNF365 protein (241-401AA)
Conjugation: Unconjugated
Alternative Names: DISC1-binding zinc-finger protein,protein su48,protein ZNF365,Su48,talanin,UAN,ZNF365D.
Involved in the regulation of neurogenesis. Negatively regulates neurite outgrowth (PubMed:17389905). Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis. Involved in the positive regulation of oligodendrocyte differentiation during postnatal growth. Involved in dendritic arborization, morphogenesis of spine density dendrite, and establishment of postsynaptic dendrite density in cortical pyramidal neurons (By similarity). Involved in homologous recombination (HR) repair pathway. Required for proper resolution of DNA double-strand breaks (DSBs) by HR. Is required for recovery of stalled replication forks, and directly contributes to genomic stability. Interacts with PARP1 and mediates MRE11-dependent DNA end resection during replication fork recovery (PubMed:23966166). Contributes to genomic stability by preventing telomere dysfunction (PubMed:23776040).
Clonality: Polyclonal
NCBI: 22891
Purity: >95%
Form: Liquid
Immunofluorescent analysis of HepG2 cells at dilution of 1:100 and Alexa Fluor 488-congug
Immunohistochemistry of paraffin-embedded human brain tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma cancer at dilution of 1:100