Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, CD14 Human, CHO, CD14 Human Recombinant, CHO
CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells.
CD14 was lyophilized from a concentrated protein solution (1.0 mg/ml) containing phosphate-buffered saline, pH 7.2. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
* VAT and and shipping costs not included. Errors and price changes excepted
