ATF4 Antibody - middle region

Catalog Number: ASB-P100913_P050
Article Name: ATF4 Antibody - middle region
Biozol Catalog Number: ASB-P100913_P050
Supplier Catalog Number: P100913_P050
Alternative Catalog Number: ASB-P100913_P050-25UL,ASB-P100913_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Canine, Human, Mouse, Porcine, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATF4
Alternative Names: CREB2, TXREB, CREB-2, TAXREB67
ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 38kDa
NCBI: 468
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-ATF4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Muscle
Host: Rabbit
Target Name: ATF4
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml
ATF4 antibody - middle region (P100913_P050) in Human Muscle using Western Blot