Synthesized peptide derived from human THRB (heavy chain, Cleaved-Ile364)
Alternative Names:
Prothrombin (EC 3.4.21.5, Coagulation factor II) [Cleaved into: Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain]
catalytic activity:Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.,disease:Defects in F2 are the cause of various forms of dysprothrombinemia [MIM:176930].,disease:Genetic variations in F2 may be a
