Synthesized peptide derived from human DFF45 (Cleaved-Ser118)
Alternative Names:
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD)
function:Inhibitor of the caspase-activated DNase (DFF40).,PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CIDE-N domain.,subunit:Heterodimer of DFFA a
