Purified recombinant fragment of human Crk-L expressed in E. Coli.
Alternative Names:
CRKL, Crk-like protein
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine ki
