In the TUNEL assay, TdT enzyme catalyzes the addition of labeled dUTP to the 3- ends of the internucleosomal DNA strand breaks that are a hallmark of apoptosis. The CF dye TUNEL Assay Apoptosis Detection Kit employs dUTP conjugated to Biotiums exceptionally bright and photostable CF fluorescent dyes, for single step fluorescent TUNEL labeling of fixed cells or tissues for analysis by fluorescence microscopy or flow cytometry. The kit is available with the following CF dyes: green fluorescent CF488A, red fluorescent CF594, and far-red fluorescent CF640R.
Source:
Animal, Synthetic
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