KIR3DL1 Polyclonal Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit

Catalog Number: BSS-BS-2421R-PE-CY5.5
Article Name: KIR3DL1 Polyclonal Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit
Biozol Catalog Number: BSS-BS-2421R-PE-CY5.5
Supplier Catalog Number: bs-2421R-PE-Cy5.5
Alternative Catalog Number: BSS-BS-2421R-PE-CY5.5-100
Manufacturer: Bioss
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human
Conjugation: PE/Cy5.5
Alternative Names: KIR3DL1, Killer cell immunoglobulin-like receptor 3DL1, AMB11, CD158 antigen-like family member E, CD158E, CD158e antigen, CD158E1, CD158E1/2, CD158E2, CL11, CL2, HLA-BW4-specic inhibitory NK cell receptor, killer cell immunoglobulin like receptor, Killer cell immunoglobulin like receptor three domains , short cytoplasmic tail, 1, Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1, KIR, KIR antigen 3DL1, KIR G1, KIR3DS1, Kirl1, Kirl2, Krl1, MGC119726, MGC119728, MGC126589, MGC126591, MHC class I NK cell receptor, Natural killer associated transcript 3, Natural killer cell inhibitory receptor, NK receptor, NK-associated transcript 10, NK-associated transcript 3, NK-associated transcript 3delIg1, NKAT10, NKAT3, NKB1, NKB1B, p70 killer cell inhibitory receptor, p70 natural killer cell receptor clones CL 2/CL 11, KI3L1_MOUSE.
KIR3DL1 (NKB1, CD158e1) is expressed on a subset of natural killer cells and T cells. NKB1 is a 70 kD member of the immunoglobulin superfamily that is expressed at varying levels among individuals. NKB1 is a type I membrane protein containing two immunoglobulin C2 type domains. The interaction of NKB1 with specific HLA B antigens on a target cell (the HLA Bw4 allele, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.
Clonality: Polyclonal
Concentration: 1ug/ul
UniProt: P83555
Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source: KLH conjugated synthetic peptide derived from mouse CD158e
Target: KIR3DL1
Application Dilute: WB(1:300-5000)