Luminespib, CAS [[747412-49-3]]
Catalog Number:
BYT-ORB1306830
Product Overview
Article Name:
Luminespib, CAS [[747412-49-3]]
Biozol Catalog Number:
BYT-ORB1306830
Supplier Catalog Number:
orb1306830
Alternative Catalog Number:
BYT-ORB1306830-5, BYT-ORB1306830-25
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
NVP-AUY 922, NVP-AUY922, NVP-AUY-922, Luminespib, inhibit, Inhibitor, Heat shock proteins, HSP, HSP90beta, HSP90alpha, Autophagy, AUY 922, AUY922, AUY-922, Apoptosis, VER52296, VER-52296, VER 52296
Product Description
Luminespib (VER-52296) is a potent and selective HSP90 inhibitor targeting both HSP90alpha and HSP90beta isoforms. It demonstrates significant antitumor activity in preclinical studies, including in vitro cell-based assays and in vivo models for head and neck squamous cell carcinoma and other malignancies.
Product Properties
Molecular Weight:
465.54
Pubmed:
41273382
Purity:
99.26% (May vary between batches)
CAS Number:
[747412-49-3]
Formula:
C26H31N3O5
Target:
Apoptosis,Autophagy,HSP
Application Notes
Application Notes:
Solubility: DMSO:16.67 mg/mL (35.81 mM),Ethanol:29 mg/mL (62.29 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:8.6 mg/mL (18.47 mM)
Images
Structure of Luminespib.
