Nilotinib, CAS [[641571-10-0]]
Catalog Number:
BYT-ORB1308331
Product Overview
Article Name:
Nilotinib, CAS [[641571-10-0]]
Biozol Catalog Number:
BYT-ORB1308331
Supplier Catalog Number:
orb1308331
Alternative Catalog Number:
BYT-ORB1308331-1,BYT-ORB1308331-100,BYT-ORB1308331-200,BYT-ORB1308331-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
Tasigna, tyrosine kinase, inhibit, Nilotinib, Inhibitor, antitumor, AMN 107, AMN107, AMN-107, Autophagy, BcrAbl, Bcr-Abl
Product Description
Nilotinib (AMN107) is an orally bioavailable, potent inhibitor of the Bcr-Abl tyrosine kinase. It demonstrates significant antitumor efficacy in both in vitro and in vivo models and is a key therapeutic agent for research on Imatinib-resistant chronic myelogenous leukemia (CML).
Product Properties
Molecular Weight:
529.52
Purity:
>99.99% (May vary between batches)
CAS Number:
[641571-10-0]
Formula:
C28H22F3N7O
Target:
Autophagy,Bcr-Abl
Application Notes
Application Notes:
Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:41.7 mg/mL (78.75 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.6 mg/mL (4.91 mM)
