Edicotinib, CAS [[1142363-52-7]]
Catalog Number:
BYT-ORB1308350
Product Overview
Article Name:
Edicotinib, CAS [[1142363-52-7]]
Biozol Catalog Number:
BYT-ORB1308350
Supplier Catalog Number:
orb1308350
Alternative Catalog Number:
BYT-ORB1308350-1,BYT-ORB1308350-10,BYT-ORB1308350-100,BYT-ORB1308350-2,BYT-ORB1308350-25,BYT-ORB1308350-5,BYT-ORB1308350-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
Inhibitor, Edicotinib, expansion, FLT3, neurodegeneration, microglial, inhibit, kit, JNJ 40346527, JNJ 527, JNJ40346527, JNJ-40346527, JNJ527, JNJ-527, colony stimulating factor 1 receptor, cKit, c-Fms, cFms, CSF-1R, CSF1R, CSF-1 receptor, alzheimers disease, arthritis, rheumatoid
Product Description
Edicotinib (JNJ-527) is a brain-penetrant, oral CSF-1R inhibitor with selectivity over KIT and FLT3. It suppresses microglial proliferation and neurodegeneration, making it a valuable research tool for studying Alzheimers disease and rheumatoid arthritis in both in vitro and in vivo models.
Product Properties
Molecular Weight:
461.6
Purity:
99.72% (May vary between batches)
CAS Number:
[1142363-52-7]
Formula:
C27H35N5O2
Target:
FLT,CSF-1R,c-Fms,c-Kit
Application Notes
Application Notes:
Solubility: DMSO:2.31 mg/mL (5 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.17 mM)
