Delgocitinib (JTE-052) is a potent pan-JAK inhibitor with selectivity for JAK1, JAK2, JAK3, and Tyk2. It is a research tool for studying cytokine signaling in inflammatory and autoimmune disease models, where it has demonstrated efficacy in suppressing pruritus and inflammation in both in vitro and in vivo experimental settings.
Molecular Weight:
310.35
Purity:
99.95% (May vary between batches)
CAS Number:
[1263774-59-9]
Formula:
C16H18N6O
Target:
Tyrosine Kinases,JAK
Application Notes:
Solubility: DMSO:240 mg/mL (773.32 mM)
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