AXL/UFO Antibody, Unconjugated, Monoclonal

Catalog Number: BYT-ORB1805936
Article Name: AXL/UFO Antibody, Unconjugated, Monoclonal
Biozol Catalog Number: BYT-ORB1805936
Supplier Catalog Number: orb1805936
Alternative Catalog Number: BYT-ORB1805936-1,BYT-ORB1805936-100
Manufacturer: Biorbyt
Category: Antikörper
Application: ELISA, FA, FACS, In vivo
Species Reactivity: Human
Conjugation: Unconjugated
Anti-AXL / UFO Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.16 kDa.
Clonality: Monoclonal
Concentration: Batch dependent
Molecular Weight: 146.22 kDa
UniProt: P30530
Buffer: 100 mM Proline/Acetic acid 20mM Arginine pH 5.0
Purity: >95%
Target: AXL / UFO
Anti-AXL / UFO Reference Antibody (tilvestamab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-AXL / UFO Reference Antibody (tilvestamab)is more than 95% ,determined by SEC-HPLC.
Immobilized human Axl FC at 2 µg/mL can bind Anti-AXL / UFO Reference Antibody (tilvestamab),EC50=0.01542µg/mL.
Human AXL HEK293 cells were stained with Anti-AXL / UFO Reference Antibody (tilvestamab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC127=0.07318 µg/mL.
The endocytosis ratio tilvestamab by U251 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40% at antibody concentration of 1 nM.
Anti-AXL / UFO Reference Antibody (tilvestamab) P-AKT Test was evaluated using U251 cell. The max induction fold was approximately 1.43.