Anti-AXL / UFO Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.16 kDa.
Anti-AXL / UFO Reference Antibody (tilvestamab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-AXL / UFO Reference Antibody (tilvestamab)is more than 95% ,determined by SEC-HPLC.
Immobilized human Axl FC at 2 µg/mL can bind Anti-AXL / UFO Reference Antibody (tilvestamab),EC50=0.01542µg/mL.
Human AXL HEK293 cells were stained with Anti-AXL / UFO Reference Antibody (tilvestamab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC127=0.07318 µg/mL.
The endocytosis ratio tilvestamab by U251 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40% at antibody concentration of 1 nM.
Anti-AXL / UFO Reference Antibody (tilvestamab) P-AKT Test was evaluated using U251 cell. The max induction fold was approximately 1.43.
* VAT and and shipping costs not included. Errors and price changes excepted