Tissue plasminogen activator from Human, Recombinant, 580,000 IU/mg
Biozol Catalog Number:
CRM-NATE-0920
Supplier Catalog Number:
NATE-0920
Alternative Catalog Number:
CRM-NATE-0920-100
Manufacturer:
Creative BioMart
Category:
Proteine/Peptide
Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine proteasewhich converts the proenzymeplasminogento plasmin, a fibrinolyticenzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migrationand tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysiswhich can result in thrombosisor embolism.
Concentration:
580,000 IU/mg
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