Synthesized peptide derived from the N-terminal region of human Cdc42EP3.
Alternative Names:
CDC42EP3, BORG2, CEP3, Cdc42 effector protein 3, Binder of Rho GTPases 2, MSE55-related Cdc42-binding protein
This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
